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M9490531.TXT
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1994-09-24
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Document 0531
DOCN M9490531
TI [Pneumocystis carinii pneumonia in HIV-infected patients examined by
bronchoscopy during the period 1989-1991]
DT 9411
AU Jensen AM; Lundgren JD; Nielsen TL; Benfield TL; Vestbo J;
Infektionsmedicinsk afdeling, Hvidovre Hospital, Kobenhavn.
SO Ugeskr Laeger. 1994 Jul 18;156(29):4241-4. Unique Identifier : AIDSLINE
MED/94345916
AB We analyzed prospectively collected data from 211 HIV-infected patients
who underwent bronchoscopy because of pulmonary symptoms during the
period 1989-1991. We found an improvement in survival for patients
diagnosed with Pneumocystis carinii pneumonia (PCP) in 1991 as compared
to 1989 and 1990 (log rank test: p = 0.07). A significant decline in PO2
and CD4 cell count was observed in patients with PCP in the same period
(p < 0.05 and 0.005 respectively). We suggest that the decline in CD4
cell count and in PO2 may reflect a change in Pneumocystis carinii
transmission, and that the improved survival may be a result of altered
treatment strategy of PCP.
DE Antigens, CD4/ANALYSIS AIDS-Related Opportunistic
Infections/*DIAGNOSIS/IMMUNOLOGY/ MORTALITY Bronchoscopy English
Abstract Female Human HIV Infections/*DIAGNOSIS/IMMUNOLOGY Male
Pneumonia, Pneumocystis carinii/*DIAGNOSIS/IMMUNOLOGY/MORTALITY
Prognosis Prospective Studies Support, Non-U.S. Gov't JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).